Since few years ago, there has been a dramatic progress in development of Artificial Intelligence (AI). This is obtained by learning ideas from the structure of human brain in which neurons are connected through a deep network of synapses. The deep artificial neural networks have shown incomparable accuracy and efficiency in learning the most complex patterns in image, video, text, voice, and also in the biology of the living organisms. PardisGene has integrated deep learning, the modern technology of using deep neural networks for solving the most complex problems, as well as many algorithmic and statistical methods in order to create a cutting-edge analysis infrastructure for genomics data. Our technology provides us the most competitive accuracy in identification of inherited and somatic (e.g. cancer-driven) variations in the genome as well as how to interpret them in order to make the most correct clinical decision.